The GJA1 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Cnx43, Connexin 43, CX43, and GJA1. This antibody recognizes Human, Mouse, and Rat antigen. The GJA1 Polyclonal Antibody has been validated for the following applications: ELISA, and Western Blot.
Description
This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia and heart malformations